anti-IL17 / IL17A antibody
anti-IL17 / IL17A antibody for ELISA,Western blot,Neutralizing,Immunohistochemistry and Human
Cancer antibody; Immune System antibody
|Product Description||Rabbit Polyclonal antibody recognizes IL17 / IL17A|
|Tested Application||ELISA, IHC, Neut, WB|
|Target Name||IL17 / IL17A|
|Immunogen||Highly pure (>98%) recombinant Human IL-17A.|
|Full Name||interleukin 17A|
|Alternate Names||IL-17A; Interleukin-17A; IL-17; CTLA8; IL17; CTLA-8; Cytotoxic T-lymphocyte-associated antigen 8|
|Application Note||IHC-P: Antigen Retrieval: pH 6.0 sodium citrate buffer (recommended)
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
|Calculated MW||18 kDa|
|Purification||Affinity purification with immunogen.|
|Buffer||PBS (pH 7.2)|
|Storage instruction||For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.|
|Note||For laboratory research only, not for drug, diagnostic or other use.|
|Gene Full Name||interleukin 17A|
|Background||The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]|
|Function||Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts. [UniProt]|
|Research Area||Cancer antibody; Immune System antibody|
|PTM||Found both in glycosylated and nonglycosylated forms.|
Images (3) Click the Picture to Zoom In
ARG20563 anti-IL17 / IL17A antibody WB image
Western blot: 250 - 0.24 ng (left to right) of recombinant Human IL-17A stained with ARG20563 anti-IL17 / IL17A antibody.
ARG20563 anti-IL17 / IL17A antibody standard curve image
Sandwich ELISA: ARG20563 anti-IL17 / IL17A antibody used as detection antibody results of a typical standard run with optical density reading at 405 - 650 nm.
ARG20563 anti-IL17 / IL17A antibody IHC image
Immunohistochemistry: formalin-fixed, paraffin-embedded sections of Human breast invasive ductal carcinoma stained with ARG20563 anti-IL17 / IL17A antibody at 0.25 µg/ml dilution (overnight incubation at 4°C). Heat induced antigen retrieval with a pH 6.0 sodium citrate buffer is recommended.