ARG20563

anti-IL17 / IL17A antibody

anti-IL17 / IL17A antibody for ELISA,Western blot,Neutralizing,Immunohistochemistry and Human

Cancer antibody; Immune System antibody

Overview

Product Description Rabbit Polyclonal antibody recognizes IL17 / IL17A
Tested Reactivity Hu
Tested Application ELISA, IHC, Neut, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name IL17 / IL17A
Species Human
Immunogen Highly pure (>98%) recombinant Human IL-17A.
Conjugation Un-conjugated
Full Name interleukin 17A
Alternate Names IL-17A; Interleukin-17A; IL-17; CTLA8; IL17; CTLA-8; Cytotoxic T-lymphocyte-associated antigen 8

Application Instructions

Application Suggestion
Tested Application Dilution
ELISA0.5 - 2.0 µg/ml
IHC0.25 µg/ml
Neut0.9 - 1.3 µg/ml
WB0.1 - 0.2 µg/ml
Application Note IHC-P: Antigen Retrieval: pH 6.0 sodium citrate buffer (recommended)
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Calculated MW 18 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS (pH 7.2)
Concentration 1 mg/ml
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 3605 Human IL17A

Swiss-port # Q16552 Human Interleukin-17A

Gene Symbol IL17A
Gene Full Name interleukin 17A
Background The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]
Function Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts. [UniProt]
Research Area Cancer antibody; Immune System antibody
PTM Found both in glycosylated and nonglycosylated forms.

Images (3) Click the Picture to Zoom In

  • ARG20563 anti-IL17 / IL17A antibody WB image

    Western blot: 250 - 0.24 ng (left to right) of recombinant Human IL-17A stained with ARG20563 anti-IL17 / IL17A antibody.

  • ARG20563 anti-IL17 / IL17A antibody standard curve image

    Sandwich ELISA: ARG20563 anti-IL17 / IL17A antibody used as detection antibody results of a typical standard run with optical density reading at 405 - 650 nm.

  • ARG20563 anti-IL17 / IL17A antibody IHC image

    Immunohistochemistry: formalin-fixed, paraffin-embedded sections of Human breast invasive ductal carcinoma stained with ARG20563 anti-IL17 / IL17A antibody at 0.25 µg/ml dilution (overnight incubation at 4°C). Heat induced antigen retrieval with a pH 6.0 sodium citrate buffer is recommended.