ARG46720

anti-IL17 / IL17A antibody

anti-IL17 / IL17A antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

Cancer antibody; Immune System antibody

Overview

Product Description Rabbit Polyclonal antibody recognizes IL17 / IL17A
Tested Reactivity Hu, Ms, Rat
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name IL17 / IL17A
Conjugation Un-conjugated
Alternate Names IL-17A; Interleukin-17A; IL-17; CTLA8; IL17; CTLA-8; Cytotoxic T-lymphocyte-associated antigen 8

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:50 - 1:200
WB1:1000 - 1:5000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity chromatography purified
Buffer PBS, Sodium azide and 50% Glycerol
Preservative Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 16171 Mouse IL17A

GeneID: 3605 Human IL17A

Swiss-port # Q16552 Human Interleukin-17A

Swiss-port # Q62386 Mouse Interleukin-17A

Gene Symbol IL17A
Gene Full Name interleukin 17A
Background The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]
Function Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts. [UniProt]
Highlight Related products:
IL17 antibodies; IL17 ELISA Kits; IL17 recombinant proteins; Anti-Rabbit IgG secondary antibodies;
Research Area Cancer antibody; Immune System antibody
Calculated MW 18 kDa
PTM Found both in glycosylated and nonglycosylated forms.

Images (5) Click the Picture to Zoom In

  • ARG46720 anti-IL17 / IL17A antibody IHC-P image

    Immunohistochemistry: Human tonsil stained with ARG46720 anti-IL17 / IL17A antibody.

  • ARG46720 anti-IL17 / IL17A antibody IHC-P image

    Immunohistochemistry: Human tonsil stained with ARG46720 anti-IL17 / IL17A antibody.

  • ARG46720 anti-IL17 / IL17A antibody IHC-P image

    Immunohistochemistry: Rat spleen stained with ARG46720 anti-IL17 / IL17A antibody.

  • ARG46720 anti-IL17 / IL17A antibody IHC-P image

    Immunohistochemistry: Mouse thymus stained with ARG46720 anti-IL17 / IL17A antibody.

  • ARG46720 anti-IL17 / IL17A antibody WB image

    Western blot: Recombinant Human IL17 / IL17A Protein stained with ARG46720 anti-IL17 / IL17A antibody.