anti-IL18 antibody

anti-IL18 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse

Cancer antibody; Immune System antibody; Metabolism antibody
publication_link Publication2


Product Description Rabbit Polyclonal antibody recognizes IL18
Tested Reactivity Hu, Ms
Tested Application FACS, IHC-P, IP, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name IL18
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 37-193 of Human IL18 (NP_001553.1).
Conjugation Un-conjugated
Alternate Names Iboctadekin; Interferon gamma-inducing factor; Interleukin-18; IL-18; IFN-gamma-inducing factor; IL-1 gamma; IGIF; IL-1g; Interleukin-1 gamma; IL1F4

Application Instructions

Application Suggestion
Tested Application Dilution
IP1:50 - 1:100
WB1:200 - 1:1000
Application Note IHC-P: PMID: 34603042 detected IL18 in paraffin-embedded ventricular tissues sections by this antibody.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control HeLa


Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 16173 Mouse IL18

GeneID: 3606 Human IL18

Swiss-port # P70380 Mouse Interleukin-18

Swiss-port # Q14116 Human Interleukin-18

Gene Symbol IL18
Gene Full Name interleukin 18
Background The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011]
Function Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. [UniProt]
Research Area Cancer antibody; Immune System antibody; Metabolism antibody
Calculated MW 22 kDa
PTM The pro-IL-18 precursor is processed by CASP1 or CASP4 to yield the active form.

Images (2) Click the Picture to Zoom In

  • ARG55332 anti-IL18 antibody WB image

    Western blot: HeLa cell lysate stained with ARG55332 anti-IL18 antibody.

  • ARG55332 anti-IL18 antibody IP image

    Immunoprecipitation: 200 µg extracts of HeLa immunoprecipitated and stained with ARG55332 anti-IL18 antibody.

Specific References

Sacubitril/Valsartan Alleviates Experimental Autoimmune Myocarditis by Inhibiting Th17 Cell Differentiation Independently of the NLRP3 Inflammasome Pathway

IHC-P / Mouse

Wei Liang et al.
Front Pharmacol.,  (2021)




Use of syngeneic cells expressing membrane-bound GM-CSF as an adjuvant to induce antibodies against native multi-pass transmembrane protein.

FACS / Mouse

Huang Chien-Chiao et al.
Sci Rep.,  (2019)