ARG47106
anti-IL31RA antibody
anti-IL31RA antibody for Western blot,ELISA and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes IL31RA |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Target Name | IL31RA |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human IL31RA. |
| Conjugation | Un-conjugated |
| Alternate Names | IL31RA; Interleukin-31 receptor subunit alpha; CRL3; GPL; Cytokine receptor-like 3; Gp130-like monocyte receptor; GLM-R; hGLM-R; Gp130-like receptor; ZcytoR17 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A |
| Buffer | PBS, 0.09% Sodium azide, 50% Glycerol and 0.5% BSA |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8NI17 Human Interleukin-31 receptor subunit alpha |
|---|---|
| Gene Symbol | IL31RA |
| Gene Full Name | interleukin 31 receptor A |
| Background | The protein encoded by this gene belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR). Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011] |
| Function | Functions as a membrane-bound signal-transducing subunit of the IL31 receptor complex (heterodimer composed of OSMR and IL31RA) which binds IL31. [UniProt] |
| Cellular Localization | Cell membrane; Membrane; Cell projection. [UniProt] |
| Calculated MW | 83 kDa |
| PTM | Glycoprotein. [UniProt] |
