ARG45757
anti-INTS4 antibody
anti-INTS4 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes INTS4 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | INTS4 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human INTS4. |
| Conjugation | Un-conjugated |
| Alternate Names | INTS4; Integrator Complex Subunit 4; MST093; INT4; MGC16733; MSTP093; Int4 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 140 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | INTS4 |
| Gene Full Name | Integrator Complex Subunit 4 |
| Background | INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008] |
| Function | Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex. [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 108 kDa |
| PTM | Acetylation; Isopeptide bond; Ubl conjugation. [UniProt] |
Images (5) Click the Picture to Zoom In
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ARG45757 anti-INTS4 antibody IHC-P image
Immunohistochemistry: Human thyroid cancer stained with ARG45757 anti-INTS4 antibody at 2 μg/ml dilution.
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ARG45757 anti-INTS4 antibody WB image
Western blot: MCF-7 stained with ARG45757 anti-INTS4 antibody at 0.5 μg/ml dilution.
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ARG45757 anti-INTS4 antibody FACS image
Flow Cytometry: MCF-7 stained with ARG45757 anti-INTS4 antibody at 1 µg/10^6 cells dilution.
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ARG45757 anti-INTS4 antibody WB image
Western blot: Rat testis stained with ARG45757 anti-INTS4 antibody at 0.5 μg/ml dilution.
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ARG45757 anti-INTS4 antibody WB image
Western blot: Mouse testis stained with ARG45757 anti-INTS4 antibody at 0.5 μg/ml dilution.
