ARG46213
anti-IQSEC1 antibody
anti-IQSEC1 antibody for Western blot,ICC/IF and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes IQSEC1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | IQSEC1 |
| Antigen Species | Human |
| Immunogen | A 19 amino acid synthetic peptide within aa. 60 - 110 of human IQSEC1. |
| Conjugation | Un-conjugated |
| Alternate Names | IQSEC1; IQ motif and Sec7 domain 1; ADP-ribosylation factors guanine nucleotide-exchange protein 100; ARFGEP100; BRAG2; Brefeldin-resistant Arf-GEF 2 protein |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 103 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -263°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q6DN90 Human IQ motif and SEC7 domain-containing protein 1 Swiss-port # Q8R0S2 Mouse IQ motif and SEC7 domain-containing protein 1 |
|---|---|
| Gene Symbol | IQSEC1 |
| Gene Full Name | IQ motif and Sec7 domain 1 |
| Background | Predicted to enable protein kinase binding activity. Predicted to be involved in several processes, including positive regulation of focal adhesion disassembly; positive regulation of keratinocyte migration; and regulation of postsynaptic neurotransmitter receptor internalization. Located in centrosome; cytosol; and nucleoplasm. Implicated in intellectual developmental disorder with short stature and behavioral abnormalities and lung adenocarcinoma. Biomarker of lung non-small cell carcinoma. [provided by Alliance of Genome Resources, Jul 2025] |
| Function | Guanine nucleotide exchange factor for ARF1 and ARF6. [UniProt] |
| Cellular Localization | Cytoplasm; Nucleus; Cytoplasmic vesicle; Cytosol. [UniProt] |
| Calculated MW | 106 kDa |
| PTM | Phosphoprotein. [UniProt] |
