ARG10313

anti-Influenza A Virus Hemagglutinin antibody [C102]

anti-Influenza A Virus Hemagglutinin antibody [C102] for ELISA,ICC/IF,IHC-Frozen sections,Western blot and Influenza A virus

Microbiology and Infectious Disease antibody

Overview

Product Description

Mouse Monoclonal antibody [C102] recognizes Influenza A Virus Hemagglutinin

Tested Reactivity Influenza A
Tested Application ELISA, ICC/IF, IHC-Fr, WB
Host Mouse
Clonality Monoclonal
Clone C102
Isotype IgG1
Target Name Influenza A Virus Hemagglutinin
Antigen Species Mouse
Immunogen Purified influenza virus type A strain H1N1 (strain: A/Kazakhstan/Seagull/470)
Conjugation Un-conjugated
Full Name hemagglutinin

Application Instructions

Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Protein G affinity purified.
Buffer PBS (pH 7.4) and 0.1% Sodium azide
Preservative 0.1% Sodium azide
Concentration 1.0-2.0 mg/ml
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Symbol HA
Gene Full Name hemagglutinin
Function Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore (By similarity). [UniProt]
Research Area Microbiology and Infectious Disease antibody

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  • ARG10313 anti-Influenza A Virus Hemagglutinin antibody [C102] ELISA image

    ELISA: Specific activity of MAb C102 in ELISA with purified virus antigen A (H1N1). MAb C102 was obtained by use of avian influenza virus strain A (H1N1) as an immunogen and it is directed against relatively conservative H1 epitope. MAb cross reactivity pattern shows that it does not react with H3 and other haemagglutinins but interacts with H1 from human and avian influenza viruses, having indirect ELISA titers not less than 1:128 K.

Clone References

Localization and force analysis at the single virus particle level using atomic force microscopy.

Liu CH et al.
Biochem Biophys Res Commun.,  (2012)

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A method to generate recombinant Salmonella typhi Ty21a strains expressing multiple heterologous genes using an improved recombineering strategy.

WB / 

Yu B et al.
Appl Microbiol Biotechnol.,  (2011)

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Electrical detection of single viruses.

Patolsky F et al.
Proc Natl Acad Sci U S A.,  (2004)

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