ARG46223
anti-JMJD1C antibody
anti-JMJD1C antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes JMJD1C |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | JMJD1C |
| Antigen Species | Human |
| Immunogen | A 20 amino acid synthetic peptide within aa. 380 - 430 of human JMJD1C. |
| Conjugation | Un-conjugated |
| Alternate Names | JMJD1C; TRIP-8; TR-interacting protein 8; Jumonji domain-containing protein 1C; Thyroid receptor-interacting protein 8; TRIP8; EC 1.14.11.-; Probable JmjC domain-containing histone demethylation protein 2C |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Purification | Affinity chromatography purified |
|---|---|
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q15652 Human Probable JmjC domain-containing histone demethylation protein 2C Swiss-port # Q69ZK6 Mouse Probable JmjC domain-containing histone demethylation protein 2C |
|---|---|
| Gene Symbol | JMJD1C |
| Gene Full Name | jumonji domain containing 1C |
| Background | JMJD1C is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. Some recently characterized members of the jmj family include JARID1A/RBP2, JARID1C, JMJD1A, JMJD1B, JMJD1C, JMJD2A, JMJD2C and JMJD2D. JMJD1C has been identified as a nuclear-receptor coactivator and is a candidate gene for autism. |
| Function | Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes (By similarity). [UniProt] |
Images (2) Click the Picture to Zoom In
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ARG46223 anti-JMJD1C antibody IHC-P image
Immunohistochemistry: Rat liver stained with ARG46223 anti-JMJD1C antibody.
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ARG46223 anti-JMJD1C antibody WB image
Western blot: Human liver stained with ARG46223 anti-JMJD1C antibody.
