ARG46236
anti-KCNK12 antibody
anti-KCNK12 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes KCNK12 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | KCNK12 |
| Antigen Species | Human |
| Immunogen | A 14 amino acid synthetic peptide within aa. 320 - 370 of human KCNK12. |
| Conjugation | Un-conjugated |
| Alternate Names | potassium channel, subfamily K, member 12; KCNK12; THIK2; THIK-2; K2p12.1; Potassium channel subfamily K member 12; Tandem pore domain halothane-inhibited potassium channel 2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -286°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9ERS1 Rat Potassium channel subfamily K member 12 Swiss-port # Q9HB15 Human Potassium channel subfamily K member 12 |
|---|---|
| Gene Symbol | KCNK12 |
| Gene Full Name | potassium channel, subfamily K, member 12 |
| Background | This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008] |
| Function | K(+) channel subunit that may homo- and heterodimerize to form functional channels with distinct regulatory and gating properties. Can heterodimerize with KCNK13 subunit to conduct K(+) outward rectifying currents at the plasma membrane. The homodimers are mainly retained in the endoplasmic reticulum compartment and may be targeted to the cell surface upon phosphorylation or other activation signals yet to be elucidated. [UniProt] |
| Cellular Localization | Cell membrane ; Endoplasmic reticulum membrane. [UniProt] |
| Calculated MW | 47 kDa |
| PTM | Glycoprotein. [UniProt] |
