ARG46222
anti-KDM3B / JMJD1B antibody
anti-KDM3B / JMJD1B antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes KDM3B / JMJD1B |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | KDM3B / JMJD1B |
| Antigen Species | Human |
| Immunogen | A 20 amino acid synthetic peptide within aa. 1050 - 1100 of human KDM3B / JMJD1B . |
| Conjugation | Un-conjugated |
| Alternate Names | KDM3B; lysine (K)-specific demethylase 3B; JMJD1B; 5qNCA; NET22; C5orf7; JMJD1B; JHDM2B; KIAA1082; Lysine-specific demethylase 3B; JmjC domain-containing histone demethylation protein 2B |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -272°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | KDM3B |
| Gene Full Name | lysine (K)-specific demethylase 3B |
| Background | Predicted to enable chromatin DNA binding activity; histone H3K9 demethylase activity; and transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleoplasm. Biomarker of acute lymphoblastic leukemia; breast cancer; colorectal cancer; and lung non-small cell carcinoma. [provided by Alliance of Genome Resources, Jul 2025] |
| Function | Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity. [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 192 kDa |
| PTM | Phosphoprotein; Isopeptide bond; Ubl conjugation; Acetylation. [UniProt] |
