ARG46240
anti-KIRREL2 antibody
anti-KIRREL2 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes KIRREL2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | KIRREL2 |
| Antigen Species | Human |
| Immunogen | A 17 amino acid synthetic peptide within aa. 550 - 600 of human KIRREL2. |
| Conjugation | Un-conjugated |
| Alternate Names | KIRREL2; kin of IRRE like 2 (Drosophila); Kin of irregular chiasm-like protein 2; Kin of IRRE-like protein 2; NEPH3; Nephrin-like protein 3; NLG1; FILTRIN |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 70 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -290°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | KIRREL2 |
| Gene Full Name | kin of IRRE like 2 (Drosophila) |
| Background | This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin (GeneID: 527362) are regulated by a bidirectional promoter. [provided by RefSeq, Jul 2016] |
| Function | May regulate basal insulin secretion. [UniProt] |
| Cellular Localization | Cell membrane. [UniProt] |
| Calculated MW | 64, 70, 78 kDa |
| PTM | Phosphoprotein; Disulfide bond; Glycoprotein. [UniProt] |
