ARG54858

anti-KIST antibody

anti-KIST antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse

Cancer antibody; Cell Biology and Cellular Response antibody; Signaling Transduction antibody

Overview

Product Description Rabbit Polyclonal antibody recognizes KIST
Tested Reactivity Hu, Ms
Predict Reactivity Rat
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name KIST
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide corresponding to aa. 1-30 (N-terminus) of Human KIST.
Conjugation Un-conjugated
Alternate Names PAM COOH-terminal interactor protein 2; KIS; Kinase interacting with stathmin; KIST; Serine/threonine-protein kinase Kist; P-CIP2; EC 2.7.11.1; U2AF homology motif kinase 1

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-PAssay-dependent
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control A549

Properties

Form Liquid
Purification Purification with Protein G.
Buffer PBS and 0.09% (W/V) Sodium azide
Preservative 0.09% (W/V) Sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 127933 Human UHMK1

GeneID: 16589 Mouse UHMK1

Swiss-port # P97343 Mouse Serine/threonine-protein kinase Kist

Swiss-port # Q8TAS1 Human Serine/threonine-protein kinase Kist

Gene Symbol UHMK1
Gene Full Name U2AF homology motif (UHM) kinase 1
Background The gene encodes a serine/threonine protein kinase that promotes cell cycle progression through G1 by phosphorylation of the cyclin-dependent kinase inhibitor 1B (p27Kip1), which causes nuclear export and degradation. The encoded protein is also thought to function in the adult nervous system and the gene has been associated with schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Function Upon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved in trafficking and/or processing of RNA (By similarity). [UniProt]
Cellular Localization Nucleus.
Research Area Cancer antibody; Cell Biology and Cellular Response antibody; Signaling Transduction antibody
Calculated MW 47 kDa

Images (1) Click the Picture to Zoom In

  • ARG54858 anti-KIST antibody WB image

    Western blot: 35 µg of A549 cell lysate stained with ARG54858 anti-KIST antibody.