anti-KMT2D / MLL2 antibody

anti-KMT2D / MLL2 antibody for Western blot and Human

Gene Regulation antibody


Product Description Rabbit Polyclonal antibody recognizes KMT2D / MLL2
Tested Reactivity Hu
Tested Application WB
Host Rabbit
Clonality Polyclonal
Target Name KMT2D / MLL2
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide corresponding to aa. 4980-5009 (C-terminus) of Human MLL2 (NP_003473.3).
Conjugation Un-conjugated
Alternate Names KABUK1; Lysine N-methyltransferase 2D; TNRC21; AAD10; MLL2; KMS; CAGL114; MLL4; Myeloid/lymphoid or mixed-lineage leukemia protein 2; EC; Histone-lysine N-methyltransferase 2D; ALR; ALL1-related protein

Application Instructions

Application Suggestion
Tested Application Dilution
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Buffer PBS and 0.09% (W/V) Sodium azide
Preservative 0.09% (W/V) Sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 8085 Human KMT2D

Swiss-port # O14686 Human Histone-lysine N-methyltransferase 2D

Gene Symbol KMT2D
Gene Full Name lysine (K)-specific methyltransferase 2D
Background The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome. [provided by RefSeq, Oct 2010]
Function Histone methyltransferase. Methylates 'Lys-4' of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription. [UniProt]
Cellular Localization Nucleus.
Research Area Gene Regulation antibody
Calculated MW 593 kDa

Images (1) Click the Picture to Zoom In

  • ARG54752 anti-KMT2D / MLL2 antibody WB image

    Western blot: 20 µg of MLL2 recombinant protein stained with ARG54752 anti-KMT2D / MLL2 antibody at 1:80000 dilution.