ARG47133
anti-LAS1L antibody
anti-LAS1L antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes LAS1L |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, IP |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Target Name | LAS1L |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human LAS1L. |
| Conjugation | Un-conjugated |
| Alternate Names | LAS1L; Ribosomal biogenesis protein LAS1L; Endoribonuclease LAS1L; Protein LAS1 homolog |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A |
| Buffer | PBS, 0.09% Sodium azide, 50% Glycerol and 0.5% BSA |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9Y4W2 Human Ribosomal biogenesis protein LAS1L |
|---|---|
| Gene Symbol | LAS1L |
| Gene Full Name | LAS1 like ribosome biogenesis factor |
| Background | Enables RNA binding activity. Involved in rRNA processing. Located in nucleolus. Part of MLL1 complex. Implicated in Wilson-Turner syndrome. [provided by Alliance of Genome Resources, Jul 2025] |
| Function | Required for the synthesis of the 60S ribosomal subunit and maturation of the 28S rRNA. [UniProt] |
| Cellular Localization | Nucleus; Cytoplasm. [UniProt] |
| Calculated MW | 83 kDa |
| PTM | Isopeptide bond; Phosphoprotein; Ubl conjugation. [UniProt] |
