ARG46254
anti-LGI2 antibody
anti-LGI2 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes LGI2 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | LGI2 |
| Antigen Species | Human |
| Immunogen | A 10 amino acid synthetic peptide within aa. 290 - 340 of human LGI2. |
| Conjugation | Un-conjugated |
| Alternate Names | leucine-rich repeat LGI family, member 2; LGI2; mKIAA1916; Kiaa1916; Leucine-rich repeat LGI family member 2; Leucine-rich glioma-inactivated protein 2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -304°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | Lgi2 |
|---|---|
| Gene Full Name | leucine-rich repeat LGI family, member 2 |
| Background | Involved in inhibitory synapse assembly. Located in extracellular space. Is expressed in several structures, including alimentary system; brain; nose; orbito-sphenoid; and salivary gland primordium. Orthologous to human LGI2 (leucine rich repeat LGI family member 2). [provided by Alliance of Genome Resources, Jul 2025] |
| Function | Required for the development of soma-targeting inhibitory GABAergic synapses made by parvalbumin-positive basket cells. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| Calculated MW | 63 kDa |
| PTM | Glycoprotein. [UniProt] |
