ARG63409
anti-LIN7B / MALS2 antibody
anti-LIN7B / MALS2 antibody for Western blot and Mouse,Rat
Cell Biology and Cellular Response antibody; Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes LIN7B / MALS2 |
|---|---|
| Tested Reactivity | Ms, Rat |
| Predict Reactivity | Hu, Cow, Dog, Pig |
| Tested Application | WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | LIN7B / MALS2 |
| Antigen Species | Human |
| Immunogen | AALVEPLGLERDVS-C |
| Conjugation | Un-conjugated |
| Alternate Names | Lin-7B; Mammalian lin-seven protein 2; hLin7B; hVeli2; MALS2; VELI2; Veli-2; MALS-2; LIN-7B; Vertebrate lin-7 homolog 2; Protein lin-7 homolog B |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by antigen affinity chromatography. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | LIN7B |
| Gene Full Name | lin-7 homolog B (C. elegans) |
| Function | Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells. May increase the amplitude of ASIC3 acid-evoked currents by stabilizing the channel at the cell surface (By similarity). [UniProt] |
| Research Area | Cell Biology and Cellular Response antibody; Signaling Transduction antibody |
| Calculated MW | 23 kDa |
Images (1) Click the Picture to Zoom In
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ARG63409 anti-LIN7B / MALS2 antibody WB image
Western blot: Rat Brain lysate (35 µg protein in RIPA buffer) stained with ARG63409 anti-LIN7B / MALS2 antibody at 0.5 µg/ml dilution.
