ARG47142
anti-LRRC25 / MAPA antibody
anti-LRRC25 / MAPA antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes LRRC25 / MAPA |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Target Name | LRRC25 / MAPA |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human LRRC25 / MAPA. |
| Conjugation | Un-conjugated |
| Alternate Names | LRRC25; Leucine-rich repeat-containing protein 25; MAPA; Monocyte and plasmacytoid-activated protein |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A |
| Buffer | PBS, 0.09% Sodium azide, 50% Glycerol and 0.5% BSA |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8N386 Human Leucine-rich repeat-containing protein 25 |
|---|---|
| Gene Symbol | LRRC25 |
| Gene Full Name | leucine rich repeat containing 25 |
| Background | Predicted to act upstream of or within several processes, including canonical NF-kappaB signal transduction; connective tissue replacement involved in inflammatory response wound healing; and response to hydrostatic pressure. Located in cytosol. [provided by Alliance of Genome Resources, Jun 2026] |
| Function | Plays a role in the inhibition of RLR-mediated type I interferon signaling pathway by targeting RIGI for autophagic degradation. Interacts specifically with ISG15-associated RIGI to promote interaction between RIGI and the autophagic cargo receptor p62/SQSTM1 to mediate RIGI degradation via selective autophagy. [UniProt] |
| Cellular Localization | Membrane; Cytoplasm. [UniProt] |
| Calculated MW | 33 kDa |
| PTM | Glycoprotein; Phosphoprotein. [UniProt] |
