ARG46269
anti-LRRFIP1 antibody
anti-LRRFIP1 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes LRRFIP1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | LRRFIP1 |
| Antigen Species | Human |
| Immunogen | A 19 amino acid synthetic peptide within the last 50 amino acids of human LRRFIP1. |
| Conjugation | Un-conjugated |
| Alternate Names | LRRFIP1; LRR FLII-interacting protein 1; TAR RNA-interacting protein; HUFI-1; TRIP; GC-binding factor 2; GCF-2; FLAP1; GCF2; Leucine-rich repeat flightless-interacting protein 1; FLAP-1; FLIIAP1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Purification | Affinity chromatography purified |
|---|---|
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q32MZ4 Human Leucine-rich repeat flightless-interacting protein 1 |
|---|---|
| Gene Symbol | LRRFIP1 |
| Gene Full Name | leucine rich repeat (in FLII) interacting protein 1 |
| Background | Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding. |
| Function | Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding. [UniProt] |
| Cellular Localization | Nucleus. Cytoplasm |
| Calculated MW | 89 kDa |
Images (2) Click the Picture to Zoom In
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ARG46269 anti-LRRFIP1 antibody IHC-P image
Immunohistochemistry: Human colon stained with ARG46269 anti-LRRFIP1 antibody.
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ARG46269 anti-LRRFIP1 antibody WB image
Western blot: Human colon stained with ARG46269 anti-LRRFIP1 antibody.
