ARG47147
anti-LSM1 antibody
anti-LSM1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes LSM1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | LSM1 |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human LSM1. |
| Conjugation | Un-conjugated |
| Alternate Names | LSM1; U6 snRNA-associated Sm-like protein LSm1; CASM; Cancer-associated Sm-like; Small nuclear ribonuclear CaSm |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A |
| Buffer | PBS, 0.09% Sodium azide, 50% Glycerol and 0.5% BSA |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O15116 Human U6 snRNA-associated Sm-like protein LSm1 |
|---|---|
| Gene Symbol | LSM1 |
| Gene Full Name | LSM1 homolog, mRNA degradation associated |
| Background | This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Nov 2011] |
| Function | Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. [UniProt] |
| Cellular Localization | Cytoplasm. [UniProt] |
| Calculated MW | 15 kDa |
| PTM | Phosphoprotein. [UniProt] |
