anti-Lipoteichoic Acid antibody [96-110]
anti-Lipoteichoic Acid antibody [96-110] for ELISA and Other
Microbiology and Infectious Disease antibody
|Product Description||Mouse Monoclonal antibody [96-110] recognizes Lipoteichoic Acid|
|Specificity||This antibody reacts with lipoteichoic acid of Staph epidermidis, Hay strain, as well as clinical strains of Staph. epidermidis (types I, II, and III), Staph. aureus strains 5 and 8, Strep. pyogenes, Strep. fecaelis, and Strep. mutans. It does not react with peptidoglycan of Staph. aureus or peptidoglycanrhamnose, nor does it react with pneumococcal polysaccharides. This antibody does not cross-react with E. coli or H. influenzae type B.|
|Target Name||Lipoteichoic Acid|
|Immunogen||Staphylococcus epidermidis, Hay strain (ATCC #55133).|
|Application Note||ELISA: use at 0.1 - 1.0 ug/ml (optimized for LTA on solid phase). Opsonization assay: use at 80 - 160 ug/ml (optimized for Staph. epidermidis, Hay strain).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
|Buffer||PBS (pH 7.4)|
|Storage Instruction||For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.|
|Note||For laboratory research only, not for drug, diagnostic or other use.|
|Background||Lipoteichoic acid (LTA) is the major proinflammatory structure present within the cell wall layer of most gram-positive bacteria. It plays an important role in the initiation and progression of bacterial infection, inflammation, and septic shock. LTA induces several cytokines in vivo, and LTA and peptidoglycan (PepG) synergize to cause the induction of nitric oxide formation which can lead to multiple organ failure. Since LTA is also found in the cell walls of non-pathogenic gram-positive bacteria, it has been suggested that the structure of LTA , and its ability to synergize with PepG, determines the ability of a particular|
|Research Area||Microbiology and Infectious Disease antibody|