ARG45531

anti-MAN2C1 antibody

anti-MAN2C1 antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes MAN2C1
Tested Reactivity Hu, Ms, Rat
Tested Application FACS, ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name MAN2C1
Antigen Species Human
Immunogen Recombinant protein containing to human MAN2C1.
Conjugation Un-conjugated
Alternate Names MAN2C1; mannosidase, alpha, class 2C, member 1; EC 3.2.1.24; MAN6A8; MANA1; Mannosidase alpha class 2C member 1; MANA; Alpha-D-mannoside mannohydrolase; Alpha-mannosidase 2C1; Alpha mannosidase 6A8B

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1 - 3 µg/10^6 cells
ICC/IF5 μg/ml
WB0.1-0.25 μg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Observed Size 100 kDa

Properties

Form Liquid
Purification Affinity purified
Buffer 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose.
Stabilizer 4% Trehalose
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 246136 Rat MAN2C1

GeneID: 4123 Human MAN2C1

GeneID: 73744 Mouse MAN2C1

Gene Symbol MAN2C1
Gene Full Name mannosidase, alpha, class 2C, member 1
Background Predicted to enable alpha-mannosidase activity. Predicted to be involved in oligosaccharide catabolic process. Located in nucleoplasm. Implicated in congenital disorder of deglycosylation 2. [provided by Alliance of Genome Resources, Feb 2025]
Function Cleaves alpha 1,2-, alpha 1,3-, and alpha 1,6-linked mannose residues on cytoplasmic free oligosaccharides generated by N-glycoprotein degradation pathways. [UniProt]
Cellular Localization Cytoplasm. [UniProt]
Calculated MW 116 kDa

Images (5) Click the Picture to Zoom In

  • ARG45531 anti-MAN2C1 antibody ICC/IF image

    Immunofluorescence: U2OS stained with ARG45531 anti-MAN2C1 antibody at 5 μg/ml dilution.

  • ARG45531 anti-MAN2C1 antibody WB image

    Western blot: HepG2 stained with ARG45531 anti-MAN2C1 antibody at 0.5 μg/ml dilution.

  • ARG45531 anti-MAN2C1 antibody FACS image

    Flow Cytometry: JK stained with ARG45531 anti-MAN2C1 antibody at 1 µg/10^6 cells dilution.

  • ARG45531 anti-MAN2C1 antibody WB image

    Western blot: PC-12 stained with ARG45531 anti-MAN2C1 antibody at 0.5 μg/ml dilution.

  • ARG45531 anti-MAN2C1 antibody WB image

    Western blot: NIH/3T3 stained with ARG45531 anti-MAN2C1 antibody at 0.5 μg/ml dilution.