ARG46281
anti-MAPKAP1 antibody
anti-MAPKAP1 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MAPKAP1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MAPKAP1 |
| Antigen Species | Human |
| Immunogen | A 19 amino acid synthetic peptide within aa. 90 - 140 of human MAPKAP1. |
| Conjugation | Un-conjugated |
| Alternate Names | mitogen-activated protein kinase associated protein 1; MAPKAP1; MIP1; SIN1; JC310; SIN1b; SIN1g; MIP1; Target of rapamycin complex 2 subunit MAPKAP1; Mitogen-activated protein kinase 2-associated protein 1; TORC2 subunit MAPKAP1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -331°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MAPKAP1 |
| Gene Full Name | mitogen-activated protein kinase associated protein 1 |
| Background | This gene encodes a protein that is highly similar to the yeast SIN1 protein, a stress-activated protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been described. Alternate polyadenylation sites as well as alternate 3' UTRs have been identified for transcripts of this gene. [provided by RefSeq, Jul 2008] |
| Function | Component of the mechanistic target of rapamycin complex 2 (mTORC2), which transduces signals from growth factors to pathways involved in proliferation, cytoskeletal organization, lipogenesis and anabolic output. [UniProt] |
| Cellular Localization | Cytoplasm; Nucleus; Cell membrane ; Endosome; Endoplasmic reticulum membrane; Lysosome membrane; Golgi apparatus; Cytosol. [UniProt] |
| Calculated MW | 59 kDa |
| PTM | Phosphoprotein; Acetylation. [UniProt] |
