ARG44867
anti-MAPRE2 / EB2 antibody
anti-MAPRE2 / EB2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse,Rat,Hamster,Monkey
Overview
| Product Description | Rat Monoclonal antibody recognizes MAPRE2 / EB2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat, Hm, Mk |
| Tested Application | IHC-P, IP, WB |
| Host | Rat |
| Clonality | Monoclonal |
| Isotype | IgG2b |
| Target Name | MAPRE2 / EB2 |
| Antigen Species | Mouse |
| Conjugation | Un-conjugated |
| Alternate Names | MAPRE2; Microtubule Associated Protein RP/EB Family Member 2; RP1; EB2; EB1; Microtubule-Associated Protein RP/EB Family Member 2; APC-Binding Protein EB1; APC-Binding Protein EB2; End-Binding Protein 2; T-Cell Activation Protein, EB1 Family; CSCSC2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MAPRE2 |
| Gene Full Name | Microtubule Associated Protein RP/EB Family Member 2 |
| Background | The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012] |
| Function | May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration. [UniProt] |
| Cellular Localization | Cytoplasm, Cytoskeleton, Microtubule. [UniProt] |
| PTM | Acetylation, Phosphoprotein. [UniProt] |
Images (3) Click the Picture to Zoom In
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ARG44867 anti-MAPRE1/EB1 antibody IHC-P image
Immunohistochemistry: Mouse brain stained with ARG44867 anti-MAPRE1/EB1 antibody at 5 µg/mL dilution.
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ARG44867 anti-MAPRE1/EB1 antibody WB image
Western blot: PMA treated Jurkat stained with ARG44867 anti-MAPRE1/EB1 antibody at 1 µg/mL dilution.
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ARG44867 anti-MAPRE1/EB1 antibody IP image
Immunoprecipitation: KT52 lysate immunoprecipitated with 2.5 µg of ARG44867 anti-MAPRE1/EB1 antibody.
