ARG47160
anti-MARCHF7 antibody
anti-MARCHF7 antibody for Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes MARCHF7 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | MARCHF7 |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human MARCHF7. |
| Conjugation | Un-conjugated |
| Alternate Names | MARCHF7; E3 ubiquitin-protein ligase MARCHF7; AXOT; MARCH7; RNF177; Axotrophin; Membrane-associated RING finger protein 7; Membrane-associated RING-CH protein VII; MARCH-VII; RING finger protein 177; RING-type E3 ubiquitin transferase MARCHF7 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A |
| Buffer | PBS, 0.09% Sodium azide, 50% Glycerol and 0.5% BSA |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9H992 Human E3 ubiquitin-protein ligase MARCH7 |
|---|---|
| Gene Symbol | MARCHF7 |
| Gene Full Name | membrane associated ring-CH-type finger 7 |
| Background | MARCH7 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Mar 2010] |
| Function | E3 ubiquitin-protein ligase which may specifically enhance the E2 activity of HIP2. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. [UniProt] |
| Cellular Localization | Cytoplasm. [UniProt] |
| Calculated MW | 78 kDa |
| PTM | Acetylation; Phosphoprotein. [UniProt] |
