ARG47176
anti-MPDZ antibody
anti-MPDZ antibody for IHC-Formalin-fixed paraffin-embedded sections and Mouse
Overview
| Product Description | Mouse Monoclonal antibody recognizes MPDZ |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | IHC-P |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Target Name | MPDZ |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human MPDZ. |
| Conjugation | Un-conjugated |
| Alternate Names | MPDZ; Multiple PDZ domain protein; MUPP1; Multi-PDZ domain protein 1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A |
| Buffer | PBS, 0.09% Sodium azide, 50% Glycerol and 0.5% BSA |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MPDZ |
| Gene Full Name | multiple PDZ domain crumbs cell polarity complex component |
| Background | The protein encoded by this gene has multiple PDZ domains, which are hallmarks of protein-protein interactions. The encoded protein is known to interact with the HTR2C receptor and may cause it to clump at the cell surface. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015] |
| Function | Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses. [UniProt] |
| Cellular Localization | Cell membrane; Membrane; Apical cell membrane; Cell projection. [UniProt] |
| Calculated MW | 222 kDa |
| PTM | Methylation; Phosphoprotein. [UniProt] |
