anti-MPO / Myeloperoxidase antibody [MPO421-8B2] (FITC)

anti-MPO / Myeloperoxidase antibody [MPO421-8B2] (FITC) for Flow cytometry and Human

Inflammatory Cell Marker antibody; Neurophil Marker antibody


Product Description FITC-conjugated Mouse Monoclonal antibody [MPO421-8B2] recognizes MPO / Myeloperoxidase
Tested Reactivity Hu
Tested Application FACS
Specificity The mouse monoclonal antibody MPO4218B2 recognizes human myeloperoxidase, a heme protein present in myeloblasts, neutrophils and monocytes. It is a marker of acute myelogenous leukemias and acute lymphoblastic leukemias.
Host Mouse
Clonality Monoclonal
Clone MPO421-8B2
Isotype IgG1
Target Name MPO / Myeloperoxidase
Antigen Species Human
Immunogen Human myeloperoxidase
Conjugation FITC
Alternate Names MPO; Myeloperoxidase; EC

Application Instructions

Application Suggestion
Tested Application Dilution
FACS4 µl / 10^6 cells
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Note The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.
Buffer PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA
Preservative 15 mM Sodium azide
Stabilizer 0.2% (w/v) high-grade protease free BSA
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 4353 Human MPO

Swiss-port # P05164 Human Myeloperoxidase

Gene Symbol MPO
Gene Full Name myeloperoxidase
Background Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014]
Function Myeloperoxidase (MPO): Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. [UniProt]
Highlight Related products:
MPO antibodies; MPO ELISA Kits; MPO Duos / Panels; Anti-Mouse IgG secondary antibodies;
Related news:
Exploring Antiviral Immune Response
Research Area Inflammatory Cell Marker antibody; Neurophil Marker antibody
Calculated MW 84 kDa

Images (1) Click the Picture to Zoom In

  • ARG65513 anti-MPO / Myeloperoxidase antibody [MPO421-8B2] (FITC) FACS image

    Flow Cytometry: Human peripheral blood stained with ARG65513 anti-MPO / Myeloperoxidase antibody [MPO421-8B2] (FITC).