ARG47178
anti-MPP8 antibody
anti-MPP8 antibody for Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes MPP8 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b |
| Target Name | MPP8 |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human MPP8. |
| Conjugation | Un-conjugated |
| Alternate Names | MPHOSPH8; M-phase phosphoprotein 8; MPP8; Two hybrid-associated protein 3 with RanBPM; Twa3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A |
| Buffer | PBS, 0.09% Sodium azide, 50% Glycerol and 0.5% BSA |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MPHOSPH8 |
| Gene Full Name | M-phase phosphoprotein 8 |
| Background | Enables chromatin binding activity and histone H3K9me2/3 reader activity. Involved in negative regulation of gene expression via chromosomal CpG island methylation; negative regulation of type I interferon production; and transposable element silencing by heterochromatin formation. Located in cytoplasm; heterochromatin; and nucleoplasm. Part of HUSH complex; HUSH2 complex; and nucleosome. Is active in chromatin and nucleus. [provided by Alliance of Genome Resources, Jun 2026] |
| Function | Heterochromatin component that specifically recognizes and binds methylated 'Lys-9' of histone H3 (H3K9me) and promotes recruitment of proteins that mediate epigenetic repression. [UniProt] |
| Cellular Localization | Nucleus; Chromosome. [UniProt] |
| Calculated MW | 97 kDa |
| PTM | Acetylation; Disulfide bond; Phosphoprotein. [UniProt] |
