ARG46298
anti-MTBP antibody
anti-MTBP antibody for Western blot,ICC/IF and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MTBP |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MTBP |
| Antigen Species | Human |
| Immunogen | A 18 amino acid synthetic peptide within aa. 110 - 160 of human MTBP. |
| Conjugation | Un-conjugated |
| Alternate Names | MTBP; MDM2 Binding Protein; MTBP; Mdm2-binding protein; hMTBP |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 104 kDa |
Properties
| Purification | Affinity chromatography purified |
|---|---|
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MTBP |
| Gene Full Name | MDM2 Binding Protein |
| Background | This gene encodes a protein that interacts with the oncoprotein mouse double minute 2. The encoded protein regulates progression through the cell cycle and may be involved in tumor formation. [provided by RefSeq, Aug 2012] |
| Function | Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells (By similarity). May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation. [UniProt] |
| Calculated MW | 104 kDa |
| PTM | Phosphoprotein. [UniProt] |
Images (2) Click the Picture to Zoom In
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ARG46298 anti-MTBP antibody ICC/IF image
Immunofluorescence: K562 stained with ARG46298 anti-MTBP antibody.
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ARG46298 anti-MTBP antibody WB image
Western blot: K562 stained with ARG46298 anti-MTBP antibody.
