ARG45654
anti-MTMR2 antibody
anti-MTMR2 antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MTMR2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MTMR2 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to N-terminal region of human MTMR2. |
| Conjugation | Un-conjugated |
| Alternate Names | MTMR2; Myotubularin Related Protein 2; KIAA1073; Phosphatidylinositol-3,5-Bisphosphate 3-Phosphatase MTMR2; Phosphatidylinositol-3-Phosphate Phosphatase; Phosphatidylinositol-3-Phosphatase; Phosphoinositide-3-Phosphatase; Myotubularin-Related Protein 2; CMT4B; Phosphatidylinositol-3,5-Bisphosphate 3-Phosphatase; EC 3.1.3.95; EC 3.1.3.48 47; EC 3.1.3.2 47; EC 3.1.3 47; CMT4B1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 73 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MTMR2 |
| Gene Full Name | Myotubularin Related Protein 2 |
| Background | This gene is a member of the myotubularin family of phosphoinositide lipid phosphatases. The encoded protein possesses phosphatase activity towards phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive demyelinating neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. [provided by RefSeq, Aug 2011] |
| Function | Lipid phosphatase that specifically dephosphorylates the D-3 position of phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate, generating phosphatidylinositol and phosphatidylinositol 5-phosphate. [UniProt] |
| Cellular Localization | Cell projection; Cytoplasm; Endosome; Membrane. [UniProt] |
| Calculated MW | 73 kDa |
| PTM | Phosphoprotein. [UniProt] |
Images (5) Click the Picture to Zoom In
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ARG45654 anti-MTMR2 antibody ICC/IF image
Immunofluorescence: Hela stained with ARG45654 anti-MTMR2 antibody at 5 μg/ml dilution.
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ARG45654 anti-MTMR2 antibody WB image
Western blot: Hela stained with ARG45654 anti-MTMR2 antibody at 0.5 μg/ml dilution.
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ARG45654 anti-MTMR2 antibody WB image
Western blot: Mouse testis stained with ARG45654 anti-MTMR2 antibody at 0.5 μg/ml dilution.
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ARG45654 anti-MTMR2 antibody FACS image
Flow Cytometry: 293T stained with ARG45654 anti-MTMR2 antibody at 1 µg/10^6 cells dilution.
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ARG45654 anti-MTMR2 antibody WB image
Western blot: Rat testis stained with ARG45654 anti-MTMR2 antibody at 0.5 μg/ml dilution.
