anti-MUC16 / CA125 antibody [X306]

anti-MUC16 / CA125 antibody [X306] for ELISA,Western blot and Human

Cancer antibody; Controls and Markers antibody; Signaling Transduction antibody


Product Description Mouse Monoclonal antibody [X306] recognizes MUC16 / CA125
Tested Reactivity Hu
Tested Application ELISA, WB
Host Mouse
Clonality Monoclonal
Clone X306
Isotype IgG1
Target Name MUC16 / CA125
Antigen Species Human
Immunogen MUC16 / CA125 antigen purified from Human ovarian carcinoma.
Conjugation Un-conjugated
Alternate Names Mucin-16; MUC-16; Ovarian carcinoma antigen CA125; CA125; Ovarian cancer-related tumor marker CA125; CA-125

Application Instructions

Application Suggestion
Tested Application Dilution
Application Note Recommended pairs for sandwich immunoassay (capture-detection):
ARG10534 - ARG10351
ARG10534 - ARG54428
ARG10534 - ARG10156

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Ion exchange chromatography
Buffer 10 mM Tris (pH 7.5), 0.15 M NaCl and 0.05 % Sodium azide
Preservative 0.05 % Sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 94025 Human MUC16

Swiss-port # Q8WXI7 Human Mucin-16

Gene Symbol MUC16
Gene Full Name mucin 16, cell surface associated
Function Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. [UniProt]
Research Area Cancer antibody; Controls and Markers antibody; Signaling Transduction antibody
Calculated MW 1519 kDa
PTM Heavily O-glycosylated; expresses both type 1 and type 2 core glycans.
Heavily N-glycosylated; expresses primarily high mannose and complex bisecting type N-linked glycans.
May be phosphorylated. Phosphorylation of the intracellular C-terminal domain may induce proteolytic cleavage and the liberation of the extracellular domain into the extracellular space.
May contain numerous disulfide bridges. Association of several molecules of the secreted form may occur through interchain disulfide bridges providing an extraordinarily large gel-like matrix in the extracellular space or in the lumen of secretory ducts.