anti-MUC6 / Gastric Mucin antibody [CLH5]

anti-MUC6 / Gastric Mucin antibody [CLH5] for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections and Human


Product Description Mouse Monoclonal antibody [CLH5] recognizes MUC6 / Gastric Mucin
Tested Reactivity Hu
Tested Application FACS, ICC/IF, IHC-P
Host Mouse
Clonality Monoclonal
Clone CLH5
Isotype IgG1, kappa
Target Name MUC6 / Gastric Mucin
Antigen Species Human
Immunogen Synthetic peptide of the gastric Mucin 6 tandem repeat sequence.
Conjugation Un-conjugated
Alternate Names Mucin-6; Gastric mucin-6; MUC-6

Application Instructions

Application Suggestion
Tested Application Dilution
FACS0.5 - 1 µg/10^6 cells in 0.1ml
ICC/IF1 - 2 µg/ml
IHC-P2 - 4 µg/ml
Application Note Antigen retrieval for IHC-P: Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min.

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Purification with Protein G.
Buffer PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA
Preservative 0.05% Sodium azide
Stabilizer 0.1 mg/ml BSA
Concentration 0.2 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 4588 Human MUC6

Swiss-port # Q6W4X9 Human Mucin-6

Gene Symbol MUC6
Gene Full Name mucin 6, oligomeric mucus/gel-forming
Background The MUC6 gene encodes gastric mucin, a secreted glycoprotein that plays an essential role in epithelial cytoprotection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract (summary by Toribara et al., 1993 [PubMed 7680650]).[supplied by OMIM, Dec 2010]
Function May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis. [UniProt]
Cellular Localization Cytoplasmic and secreted
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Calculated MW 257 kDa
PTM O-glycosylated.

Images (1) Click the Picture to Zoom In

  • ARG56062 anti-MUC6 / Gastric Mucin antibody [CLH5] IHC-P image

    Immunohistochemistry: Formalin-fixed, paraffin-embedded Human gastric carcinoma stained with ARG56062 anti-MUC6 / Gastric Mucin antibody [CLH5].