ARG46286
anti-Melanocortin 4 Receptor antibody
anti-Melanocortin 4 Receptor antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Melanocortin 4 Receptor |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Melanocortin 4 Receptor |
| Antigen Species | Human |
| Immunogen | A 19 amino acid synthetic peptide within the first 50 amino acids of human Melanocortin 4 Receptor. |
| Conjugation | Un-conjugated |
| Alternate Names | MC4R; MC4-R; MC4R; Melanocortin receptor 4 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Purification | Affinity chromatography purified |
|---|---|
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MC4R |
| Gene Full Name | melanocortin 4 receptor |
| Background | The protein encoded by this gene is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity. [provided by RefSeq, Jan 2010] |
| Function | Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP). [UniProt] |
| Cellular Localization | Cell membrane; Multi-pass membrane protein [UniProt] |
| Calculated MW | 37 kDa |
Images (3) Click the Picture to Zoom In
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ARG46286 anti-Melanocortin 4 Receptor antibody IHC-P image
Immunohistochemistry: Human brain stained with ARG46286 anti-Melanocortin 4 Receptor antibody.
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ARG46286 anti-Melanocortin 4 Receptor antibody ICC/IF image
Immunofluorescence: Human brain cell stained with ARG46286 anti-Melanocortin 4 Receptor antibody.
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ARG46286 anti-Melanocortin 4 Receptor antibody WB image
Western blot: Rat brain stained with ARG46286 anti-Melanocortin 4 Receptor antibody.
