ARG59975
anti-Munc18c antibody
anti-Munc18c antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Munc18c |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Munc18c |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 343-592 of Human Munc18c (NP_009200.2). |
| Conjugation | Un-conjugated |
| Alternate Names | Unc18-3; Protein unc-18 homolog C; MUNC18-3; Syntaxin-binding protein 3; Platelet Sec1 protein; Protein unc-18 homolog 3; Unc-18C; PSP; MUNC18C; UNC-18C |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Rat brain, Mouse brain and Jurkat | ||||
| Observed Size | 68 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | STXBP3 |
| Gene Full Name | syntaxin binding protein 3 |
| Function | Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes. [UniProt] |
| Cellular Localization | Cytoplasm, cytosol. Cell membrane. Note=In platelets, predominantly cytosolic. Low amounts membrane-associated. [UniProt] |
| Calculated MW | 68 kDa |
| PTM | Phosphorylated by PKC in platelets in response to thrombin stimulation; phosphorylation inhibits binding to STX4. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG59975 anti-Munc18c antibody WB image
Western blot: 25 µg of Rat brain, Mouse brain and Jurkat cell lysates stained with ARG59975 anti-Munc18c antibody at 1:1000 dilution.
