ARG46309
anti-NALP14 antibody
anti-NALP14 antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes NALP14 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NALP14 |
| Antigen Species | Human |
| Immunogen | A 16 amino acid synthetic peptide within aa. 200 - 250 of human NALP14. |
| Conjugation | Un-conjugated |
| Alternate Names | NLRP14; NLR family, pyrin domain containing 14; NALP14; NOD5; PAN8; GC-LRR; NALP14; CLR11.2; NOD5; NACHT; LRR and PYD domains-containing protein 14; Nucleotide-binding oligomerization domain protein 5 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -359°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q6B966 Mouse NACHT, LRR and PYD domains-containing protein 14 Swiss-port # Q86W24 Human NACHT, LRR and PYD domains-containing protein 14 |
|---|---|
| Gene Symbol | NLRP14 |
| Gene Full Name | NLR family, pyrin domain containing 14 |
| Background | The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq, Jul 2008] |
| Function | May be involved in inflammation and spermatogenesis. [UniProt] |
| Cellular Localization | Cytoplasm. [UniProt] |
| Calculated MW | 125 kDa |
