ARG46313
anti-NALP7 antibody
anti-NALP7 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes NALP7 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NALP7 |
| Antigen Species | Human |
| Immunogen | A 18 amino acid synthetic peptide within aa. 90 - 140 of human NALP7. |
| Conjugation | Un-conjugated |
| Alternate Names | NLRP7; NLR family, pyrin domain containing 7; NALP7; HYDM; PAN7; NALP7; NOD12; PYPAF3; CLR19.4; NACHT; LRR and PYD domains-containing protein 7; Nucleotide-binding oligomerization domain protein 12 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -363°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8WX94 Human NACHT, LRR and PYD domains-containing protein 7 |
|---|---|
| Gene Symbol | NLRP7 |
| Gene Full Name | NLR family, pyrin domain containing 7 |
| Background | This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| Function | Inhibits CASP1/caspase-1-dependent IL1B secretion. [UniProt] |
| Calculated MW | 112 kDa |
