ARG46314
anti-NALP8 antibody
anti-NALP8 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes NALP8 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NALP8 |
| Antigen Species | Human |
| Immunogen | A 16 amino acid synthetic peptide within aa. 130 - 180 of human NALP8. |
| Conjugation | Un-conjugated |
| Alternate Names | NLRP8; NLR family, pyrin domain containing 8; NALP8; PAN4; NALP8; NOD16; CLR19.2; PAN4; NACHT; LRR and PYD domains-containing protein 8; Nucleotide-binding oligomerization domain protein 16 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -364°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q86W28 Human NACHT, LRR and PYD domains-containing protein 8 |
|---|---|
| Gene Symbol | NLRP8 |
| Gene Full Name | NLR family, pyrin domain containing 8 |
| Background | This gene encodes a member of the nucleotide-binding oligomerization domain/ leucine rich repeat/ pyrin domain containing (NLRP) subfamily, which belongs to the Nod-like receptor family of proteins. NLRP genes play roles in the mammalian innate immune system through inflammasome formation and activation of caspases. In addition, NLRP genes have been found to function during mammalian reproduction. Consistent with a function during human preimplantation development, this gene is expressed at high levels in oocytes with decreased levels in embryos. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016] |
| Function | Involved in inflammation. [UniProt] |
| Cellular Localization | Cytoplasm. [UniProt] |
| Calculated MW | 119 kDa |
