ARG46754

anti-NCOA4 antibody

anti-NCOA4 antibody for Flow cytometry,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes NCOA4
Tested Reactivity Hu, Ms, Rat
Tested Application FACS, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name NCOA4
Antigen Species Human
Immunogen Recombinant protein of Human NCOA4
Conjugation Un-conjugated
Alternate Names Ret-activating protein ELE1; Androgen receptor coactivator 70 kDa protein; Androgen receptor-associated protein of 70 kDa; Nuclear receptor coactivator 4; 70 kDa androgen receptor coactivator; ELE1; RFG; ARA70; 70 kDa AR-activator; PTC3; NCoA-4

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1 - 3 µg/10^6 cells
WB0.25 - 0.5 μg/mL
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Observed Size ~70 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen
Purification Note Boster
Purity A04368-3
Buffer 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose.
Stabilizer 4% Trehalose
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 8031 Human NCOA4

Swiss-port # Q13772 Human Nuclear receptor coactivator 4

Gene Symbol NCOA4
Gene Full Name nuclear receptor coactivator 4
Background This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14. [provided by RefSeq, Feb 2009]
Function Enhances the androgen receptor transcriptional activity in prostate cancer cells. Ligand-independent coactivator of the peroxisome proliferator-activated receptor (PPAR) gamma. [UniProt]
Calculated MW ~70 kDa