ARG45703
anti-NDRG4 antibody
anti-NDRG4 antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes NDRG4 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NDRG4 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human NDRG4. |
| Conjugation | Un-conjugated |
| Alternate Names | NDRG4; NDRG Family Member 4; SMAP-8; KIAA1180; Vascular Smooth Muscle Cell-Associated Protein 8; N-Myc Downstream-Regulated Gene 4 Protein; Brain Development-Related Molecule 1; Protein NDRG4; BDM1; Smooth Muscle-Associated Protein 8; SMAP8 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 37 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | NDRG4 |
| Gene Full Name | NDRG Family Member 4 |
| Background | This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that is required for cell cycle progression and survival in primary astrocytes and may be involved in the regulation of mitogenic signalling in vascular smooth muscles cells. Alternative splicing results in multiple transcripts encoding different isoforms.[provided by RefSeq, Jun 2011] |
| Function | Contributes to the maintenance of intracerebral BDNF levels within the normal range, which is necessary for the preservation of spatial learning and the resistance to neuronal cell death caused by ischemic stress (By similarity). May enhance growth factor-induced ERK1 and ERK2 phosphorylation, including that induced by PDGF and FGF. May attenuate NGF-promoted ELK1 phosphorylation in a microtubule-dependent manner. [UniProt] |
| Cellular Localization | Cytoplasm. [UniProt] |
| Calculated MW | 38 kDa |
| PTM | Phosphoprotein. [UniProt] |
Images (5) Click the Picture to Zoom In
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ARG45703 anti-NDRG4 antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG45703 anti-NDRG4 antibody at 5 μg/ml dilution.
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ARG45703 anti-NDRG4 antibody WB image
Western blot: 293T stained with ARG45703 anti-NDRG4 antibody at 0.5 μg/ml dilution.
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ARG45703 anti-NDRG4 antibody FACS image
Flow Cytometry: 293T stained with ARG45703 anti-NDRG4 antibody at 1 µg/10^6 cells dilution.
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ARG45703 anti-NDRG4 antibody WB image
Western blot: Rat brain stained with ARG45703 anti-NDRG4 antibody at 0.5 μg/ml dilution.
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ARG45703 anti-NDRG4 antibody WB image
Western blot: Mouse brain stained with ARG45703 anti-NDRG4 antibody at 0.5 μg/ml dilution.
