ARG46321
anti-NDST1 antibody
anti-NDST1 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes NDST1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NDST1 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide near the amino terminus of human NDST1. |
| Conjugation | Un-conjugated |
| Alternate Names | N-deacetylase and N-sulfotransferase 1; NDST1; HSST; NST1; MRT46 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Observed Size | 97 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -371°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | NDST1 |
|---|---|
| Gene Full Name | N-deacetylase and N-sulfotransferase 1 |
| Background | Enables N-acetylglucosamine deacetylase activity; heparan sulfate N-deacetylase activity; and heparan sulfate N-sulfotransferase activity. Involved in heparan sulfate proteoglycan biosynthetic process. Acts upstream of or within several processes, including circulatory system development; embryonic cranial skeleton morphogenesis; and positive regulation of signal transduction. Is active in Golgi apparatus. Is expressed in several structures, including exocrine system; future brain; integumental system; nervous system; and respiratory system. Used to study DiGeorge syndrome; congenital diaphragmatic hernia; and newborn respiratory distress syndrome. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 46. Orthologous to human NDST1 (N-deacetylase and N-sulfotransferase 1). [provided by Alliance of Genome Resources, Jul 2025] |
| Function | [Isoform 1]: Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. [UniProt] |
| Cellular Localization | Golgi apparatus. [UniProt] |
| Calculated MW | 97 kDa |
| PTM | Disulfide bond; Glycoprotein. [UniProt] |
