ARG46322
anti-NDST2 antibody
anti-NDST2 antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes NDST2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NDST2 |
| Antigen Species | Human |
| Immunogen | A 16 amino acid synthetic peptide within aa. 20 - 70 of human NDST2. |
| Conjugation | Un-conjugated |
| Alternate Names | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2; NDST2; NST2; HSST2; N-heparan sulfate sulfotransferase 2; NDST-2 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Observed Size | 101 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -372°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P52849 Human Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 Swiss-port # P52850 Mouse Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 |
|---|---|
| Gene Symbol | NDST2 |
| Gene Full Name | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| Background | This gene encodes a member of the N-deacetylase/N-sulfotransferase subfamily of the sulfotransferase 1 proteins. The encoded enzyme has dual functions in processing glucosamine and heparin polymers, including N-deacetylation and N-sulfation. The encoded protein may be localized to the Golgi. [provided by RefSeq, Feb 2009] |
| Function | Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Required for the exosomal release of SDCBP, CD63 and syndecan. [UniProt] |
| Cellular Localization | Golgi apparatus. [UniProt] |
| Calculated MW | 97 kDa |
| PTM | Disulfide bond; Glycoprotein. [UniProt] |
