ARG47194
anti-NECAB2 antibody
anti-NECAB2 antibody for Immunoprecipitation,Western blot and Rat
Overview
| Product Description | Mouse Monoclonal antibody recognizes NECAB2 |
|---|---|
| Tested Reactivity | Rat |
| Tested Application | IP, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Target Name | NECAB2 |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human NECAB2. |
| Conjugation | Un-conjugated |
| Alternate Names | NECAB2; N-terminal EF-hand calcium-binding protein 2; EFCBP2; Neuronal calcium-binding protein 2; Synaptotagmin-interacting protein 2; Stip-2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A |
| Buffer | PBS, 0.09% Sodium azide, 50% Glycerol and 0.5% BSA |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | NECAB2 |
|---|---|
| Gene Full Name | N-terminal EF-hand calcium binding protein 2 |
| Background | The protein encoded by this gene is a neuronal calcium-binding protein that binds to and modulates the function of at least two receptors, adenosine A(2A) receptor and metabotropic glutamate receptor type 5. [provided by RefSeq, Jul 2016] |
| Function | May act as a signaling scaffold protein that senses intracellular calcium. Can modulate ligand-induced internalization of ADORA2A and coupling efficiency of mGluR5/GRM5; for both receptors may regulate signaling activity such as promoting MAPK1/3 (ERK1/2) activation. [UniProt] |
| Cellular Localization | Cytoplasm; Cell projection; Cell membrane; Membrane. [UniProt] |
| Calculated MW | 43 kDa |
| PTM | Methylation. [UniProt] |
