ARG46323
anti-NETO1 antibody
anti-NETO1 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes NETO1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NETO1 |
| Antigen Species | Human |
| Immunogen | A 18 amino acid synthetic peptide within aa. 350 - 400 of human NETO1. |
| Conjugation | Un-conjugated |
| Alternate Names | NETO1; Neuropilin And Tolloid Like 1; BTCL1; BCTL1; Brain-Specific Transmembrane Protein Containing 2 CUB And 1 LDL-Receptor Class A Domains Protein 1; Neuropilin (NRP) And Tolloid (TLL)-Like 1; Neuropilin And Tolloid-Like Protein 1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 60 kDa |
Properties
| Purification | Affinity chromatography purified |
|---|---|
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8R4I7 Mouse Neuropilin and tolloid-like protein 1 Swiss-port # Q8TDF5 Human Neuropilin and tolloid-like protein 1 |
|---|---|
| Gene Symbol | NETO1 |
| Gene Full Name | Neuropilin And Tolloid Like 1 |
| Background | This gene encodes a transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. This protein is thought to play a critical role in spatial learning and memory by regulating the function of synaptic N-methyl-D-aspartic acid receptor complexes in the hippocampus. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2017] |
| Function | Involved in the development and/or maintenance of neuronal circuitry. Accessory subunit of the neuronal N-methyl-D-aspartate receptor (NMDAR) critical for maintaining the abundance of GRIN2A-containing NMDARs in the postsynaptic density. Regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory. [Uniprot] |
| Cellular Localization | Cell membrane, Membrane, Postsynaptic cell membrane, Secreted, Synapse. [Uniprot] |
| Calculated MW | 60 kDa |
| PTM | Disulfide bond, Glycoprotein, Phosphoprotein. [Uniprot] |
Images (2) Click the Picture to Zoom In
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ARG46323 anti-NETO1 antibody IHC-P image
Immunohistochemistry: Rat lung stained with ARG46323 anti-NETO1 antibody.
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ARG46323 anti-NETO1 antibody WB image
Western blot: Human brain stained with ARG46323 anti-NETO1 antibody.
