ARG47198
anti-NKIRAS1 antibody
anti-NKIRAS1 antibody for Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes NKIRAS1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Target Name | NKIRAS1 |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human NKIRAS1. |
| Conjugation | Un-conjugated |
| Alternate Names | NKIRAS1; NF-kappa-B inhibitor-interacting Ras-like protein 1; KBRAS1; I-kappa-B-interacting Ras-like protein 1; Kappa B-Ras protein 1; KappaB-Ras1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A |
| Buffer | PBS, 0.09% Sodium azide, 50% Glycerol and 0.5% BSA |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9NYS0 Human NF-kappa-B inhibitor-interacting Ras-like protein 1 |
|---|---|
| Gene Symbol | NKIRAS1 |
| Gene Full Name | NFKB inhibitor interacting Ras like 1 |
| Background | Predicted to enable GTPase activating protein binding activity. Predicted to be involved in Ral protein signal transduction. Predicted to act upstream of or within lung alveolus development; regulation of tumor necrosis factor-mediated signaling pathway; and surfactant homeostasis. Located in cytosol. [provided by Alliance of Genome Resources, Jun 2026] |
| Function | Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB. [UniProt] |
| Cellular Localization | Cytoplasm. [UniProt] |
| Calculated MW | 22 kDa |
