ARG46333
anti-NLRC3 antibody
anti-NLRC3 antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes NLRC3 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NLRC3 |
| Antigen Species | Human |
| Immunogen | A 18 amino acid synthetic peptide within aa. 630 - 680 of human NLRC3. |
| Conjugation | Un-conjugated |
| Alternate Names | NLR family, CARD domain containing 3; NOD3; NOD3; CLR16.2; NOD3; Protein NLRC3; CARD15-like protein |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -383°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | NLRC3 |
| Gene Full Name | NLR family, CARD domain containing 3 |
| Background | This gene encodes a NOD-like receptor family member. The encoded protein is a cytosolic regulator of innate immunity. This protein directly interacts with stimulator of interferon genes (STING), to prevent its proper trafficking, resulting in disruption of STING-dependent activation of the innate immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] |
| Function | Negative regulator of the innate immune response. [UniProt] |
| Cellular Localization | Cytoplasm. [UniProt] |
| Calculated MW | 115 kDa |
