ARG46334

anti-NLRC5 antibody

anti-NLRC5 antibody for Western blot,ICC/IF and Human,Mouse

Overview

Product Description Rabbit Polyclonal antibody recognizes NLRC5
Tested Reactivity Hu, Ms
Tested Application ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name NLRC5
Antigen Species Human
Immunogen A 18 amino acid synthetic peptide within aa. 20 - 70 of human NLRC5.
Conjugation Un-conjugated
Alternate Names NLR family, CARD domain containing 5; NOD4; NOD4; NOD27; CLR16.1; NOD4; Protein NLRC5; Nucleotide-binding oligomerization domain protein 27

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IFAssay-dependent
WBAssay-dependent
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity chromatography purified
Buffer PBS and 0.02% Sodium azide.
Preservative 0.02% Sodium azide
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -384°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 434341 Mouse NLRC5

GeneID: 84166 Human NLRC5

Swiss-port # C3VPR6 Mouse Protein NLRC5

Swiss-port # Q86WI3 Human Protein NLRC5

Gene Symbol NLRC5
Gene Full Name NLR family, CARD domain containing 5
Background This gene encodes a member of the caspase recruitment domain-containing NLR family. This gene plays a role in cytokine response and antiviral immunity through its inhibition of NF-kappa-B activation and negative regulation of type I interferon signaling pathways. [provided by RefSeq, Oct 2011]
Function Probable regulator of the NF-kappa-B and type I interferon signaling pathways. May also regulate the type II interferon signaling pathway. Plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms. [UniProt]
Cellular Localization Cytoplasm. [UniProt]
Calculated MW 205 kDa