anti-NOX1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
|Product Description||Rabbit Polyclonal antibody recognizes NOX1|
|Tested Application||IHC-P, WB|
|Immunogen||Synthetic peptide corresponding to aa. 354-374 of Human NOX1. (HIRAAGDWTENLIRAFEQQYS)|
|Alternate Names||NOH1; GP91-2; NOX-1; NADPH oxidase 1; MOX-1; Mitogenic oxidase 1; MOX1; EC 1.-.-.-; NOH-1; NADH/NADPH mitogenic oxidase subunit P65-MOX|
|Application Note||IHC-P: Antigen Retrieval: Heat mediation was recommended.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
|Purification||Affinity purification with immunogen.|
|Buffer||0.2% Na2HPO4, 0.9% NaCl, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA.|
|Preservative||0.05% Thimerosal and 0.05% Sodium azide|
|Storage Instruction||For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.|
|Note||For laboratory research only, not for drug, diagnostic or other use.|
|Gene Full Name||NADPH oxidase 1|
|Background||This gene encodes a member of the NADPH oxidase family of enzymes responsible for the catalytic one-electron transfer of oxygen to generate superoxide or hydrogen peroxide. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]|
|Function||NOH-1S is a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes and other tissues. It participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain. [UniProt]|
|Cellular Localization||Cell projection, invadopodium membrane; Multi-pass membrane protein. Cell membrane. [UniProt]|
|Calculated MW||65 kDa|
Images (2) Click the Picture to Zoom In
ARG59887 anti-NOX1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human lung cancer tissue stained with ARG59887 anti-NOX1 antibody.
ARG59887 anti-NOX1 antibody WB image
Western blot: 40 µg of HeLa and MCF7 whole cell lysates stained with ARG59887 anti-NOX1 antibody at 0.5 µg/ml dilution.