ARG44172
anti-NTHL1 antibody
anti-NTHL1 antibody for Flow cytometry,ICC/IF,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes NTHL1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NTHL1 |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human NTHL1 |
| Conjugation | Un-conjugated |
| Protein Full Name | Endonuclease III-like protein 1 |
| Alternate Names | NTHL1; Nth Like DNA Glycosylase 1; OCTS3; NTH1; Bifunctional DNA N-Glycosylase/DNA-(Apurinic Or Apyrimidinic Site) Lyase; Endonuclease III-Like Protein 1; DNA Glycosylase/AP Lyase; HNTH1; Bifunctional DNA N-Glycoslyase/DNA-(Apurinic Or Apyrimidinic Site) Lyase; Nth Endonuclease III-Like 1 (E. Coli); Nth (E.Coli Endonuclease III)-Like 1; Nth Endonuclease III-Like 1; DNA Glycoslyase/AP Lyase; EC 4.2.99.18; EC 3.2.2.- ; FAP3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | NTHL1 |
| Gene Full Name | Nth Like DNA Glycosylase 1 |
| Background | The protein encoded by this gene is a DNA N-glycosylase of the endonuclease III family. Like a similar protein in E. coli, the encoded protein has DNA glycosylase activity on DNA substrates containing oxidized pyrimidine residues and has apurinic/apyrimidinic lyase activity. |
| Function | Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. |
| Cellular Localization | Mitochondrion, Nucleus |
| Calculated MW | 34 kDa |
| PTM | Phosphoprotein, Ubl conjugation |
Images (3) Click the Picture to Zoom In
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ARG44172 anti-NTHL1 antibody ICC/IF image
Immunofluorescence: HeLa stained with ARG44172 anti-NTHL1 antibody at 5 μg/mL dilution.
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ARG44172 anti-NTHL1 antibody WB image
Western blot: 293T and HeLa stained with ARG44172 anti-NTHL1 antibody at 0.5 μg/mL dilution.
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ARG44172 anti-NTHL1 antibody FACS image
Flow Cytometry: MCF-7 stained with ARG44172 anti-NTHL1 antibody at 1 μg/1x10^6 cells dilution.
