ARG47203
anti-NUDT3 / DIPP antibody
anti-NUDT3 / DIPP antibody for Western blot and Mouse
Overview
| Product Description | Mouse Polyclonal antibody recognizes NUDT3 / DIPP |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NUDT3 / DIPP |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human NUDT3 / DIPP. |
| Conjugation | Un-conjugated |
| Alternate Names | NUDT3; Diphosphoinositol polyphosphate phosphohydrolase 1; DIPP; DIPP1; Diadenosine hexaphosphate hydrolase; Ap6A hydrolase; Endopolyphosphatase; Nucleoside diphosphate-linked moiety X motif 3; Nudix motif 3; m7GpppN-mRNA hydrolase; m7GpppX diphosphatase |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS, 0.09% Sodium azide, 50% Glycerol and 0.5% BSA |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9JI46 Mouse Diphosphoinositol polyphosphate phosphohydrolase 1 |
|---|---|
| Gene Symbol | NUDT3 |
| Gene Full Name | nudix hydrolase 3 |
| Background | NUDT3 belongs to the MutT, or Nudix, protein family. Nudix proteins act as homeostatic checkpoints at important stages in nucleoside phosphate metabolic pathways, guarding against elevated levels of potentially dangerous intermediates, like 8-oxo-dGTP, which promotes AT-to-CG transversions (Safrany et al., 1998 [PubMed 9822604]).[supplied by OMIM, Feb 2011] |
| Function | Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate) and [PP]2-InsP4 (bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction. [UniProt] |
| Cellular Localization | Cytoplasm; Nucleus. [UniProt] |
| Calculated MW | 19 kDa |
| PTM | Acetylation. [UniProt] |
