ARG45676
anti-NUP43 antibody
anti-NUP43 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes NUP43 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NUP43 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human NUP43. |
| Conjugation | Un-conjugated |
| Alternate Names | NUP43; Nucleoporin 43; BA350J20.1; Nup107-160 Subcomplex Subunit Nup43; Nucleoporin 43kDa; Nucleoporin Nup43; FLJ13287; P42 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 42 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | NUP43 |
| Gene Full Name | Nucleoporin 43 |
| Background | Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP43 is part of one such subcomplex, Nup107-160 (Loiodice et al., 2004 [PubMed 15146057]).[supplied by OMIM, Mar 2008] |
| Function | Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. [UniProt] |
| Cellular Localization | Centromere; Chromosome; Kinetochore; Nuclear pore complex; Nucleus. [UniProt] |
| Calculated MW | 42 kDa |
| PTM | Acetylation. [UniProt] |
Images (6) Click the Picture to Zoom In
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ARG45676 anti-NUP43 antibody IHC-P image
Immunohistochemistry: Human liver cancer stained with ARG45676 anti-NUP43 antibody at 2 μg/ml dilution.
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ARG45676 anti-NUP43 antibody ICC/IF image
Immunofluorescence: A549 stained with ARG45676 anti-NUP43 antibody at 5 μg/ml dilution.
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ARG45676 anti-NUP43 antibody WB image
Western blot: K562 stained with ARG45676 anti-NUP43 antibody at 0.5 μg/ml dilution.
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ARG45676 anti-NUP43 antibody FACS image
Flow Cytometry: K562 stained with ARG45676 anti-NUP43 antibody at 1 µg/10^6 cells dilution.
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ARG45676 anti-NUP43 antibody IHC-P image
Immunohistochemistry: Rat brain stained with ARG45676 anti-NUP43 antibody at 2 μg/ml dilution.
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ARG45676 anti-NUP43 antibody IHC-P image
Immunohistochemistry: Mouse brain stained with ARG45676 anti-NUP43 antibody at 2 μg/ml dilution.
