ARG46319
anti-Nicalin antibody
anti-Nicalin antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Nicalin |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Nicalin |
| Antigen Species | Human |
| Immunogen | A 18 amino acid synthetic peptide within aa. 390 - 440 of human Nicalin. |
| Conjugation | Un-conjugated |
| Alternate Names | NCLN; Nicalin; Nicastrin-Like Protein; NET59; BOS Complex Subunit NCLN; Nicalin Homolog (Zebrafish); Nicalin Homolog |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Purification | Affinity chromatography purified |
|---|---|
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | NCLN |
| Gene Full Name | nicalin |
| Background | Enables ribosome binding activity. Involved in several processes, including multi-pass transmembrane protein insertion into ER membrane; protein stabilization; and regulation of protein complex stability. Located in endoplasmic reticulum membrane. Part of multi-pass translocon complex. [provided by Alliance of Genome Resources, Feb 2025] |
| Function | Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes. [UniProt] |
| Cellular Localization | Endoplasmic reticulum; Membrane. [UniProt] |
| Calculated MW | 63 kDa |
| PTM | Glycoprotein. [UniProt] |
Images (2) Click the Picture to Zoom In
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ARG46319 anti-Nicalin antibody IHC-P image
Immunohistochemistry: Human heart stained with ARG46319 anti-Nicalin antibody.
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ARG46319 anti-Nicalin antibody WB image
Western blot: Mouse heart stained with ARG46319 anti-Nicalin antibody.
